CD3 eta/phi

 Normal cellularity and subset composition in thymus and peripheral lymphoid organs
 Normal alloproliferative responses
 Normal cytotoxic T lymphocyte generation and effector function

Koyasu et al., 1994


METHODOLOGY ( FROM T-BASE)

((cd3 eta/phi))

Line Name DNA Construct
1. CD3 Nef1 #1 The CD3 Nef1 expression vector contains the HIV-1 NL43 nef cloned at XbaI site downstream of the CD3 enhancer/promoter elements in the pNEZ vector and followe....
2. CD3 Nef1 #3.1 The CD3 Nef1 expression vector contains the HIV-1 NL43 nef cloned at XbaI site downstream of the CD3 enhancer/promoter elements in the pNEZ vector and followe....
3. CD3 Nef1 #4 The CD3 Nef1 expression vector contains the HIV-1 NL43 nef cloned at XbaI site downstream of the CD3 enhancer/promoter elements in the pNEZ vector and followe....
4. TCR CD3-eta (+/-) The targeting vector was made up of a long arm (a 6-kb genomic fragment containing exons 7 and 8 of the zeta/eta gene), a neo gene expression cassette from pMC1neo, a sh....
5. CD3 Nef1 #5.2 The CD3 Nef1 expression vector contains the HIV-1 NL43 nef cloned at XbaI site downstream of the CD3 enhancer/promoter elements in the pNEZ vector and followe....
6. CD3 Nef1 #2.2 The CD3 Nef1 expression vector contains the HIV-1 NL43 nef cloned at XbaI site downstream of the CD3 enhancer/promoter elements in the pNEZ vector and followe....
7. CD3 Nef1 #3.2 The CD3 Nef1 expression vector contains the HIV-1 NL43 nef cloned at XbaI site downstream of the CD3 enhancer/promoter elements in the pNEZ vector and followe....
8. TCR CD3-eta (-/-) The targeting vector was made up of a long arm (a 6-kb genomic fragment containing exons 7 and 8 of the zeta/eta gene), a neo gene expression cassette from pMC1neo, a sh....
9. TCR CD3-eta (+/-) a To generate the eta-T mutation, the targeting vector consisted of a long arm (a 6-kb genomic fragment containing exons 7 and 8 of the zeta/eta gene), a neo gene express....
10. TCR CD3-eta (-/-) a


Database links: CD3H

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