CRH

Normal growth
Normal fertility
Normal longevity
Marked glucocorticoid deficiency
Impaired lung maturation

Muglia et al., 1995

((crh))

	Line Name	DNA Construct
1.	CRH (+/-)	Homologous recombination results in replacement of the entire pre-pro-CRH (corticotropin-releasing hormone) coding region with the neomycin resistance gene.
2.	CRH (-/-)	Homologous recombination results in replacement of the entire pre-pro-CRH (corticotropin-releasing hormone) coding region with the neomycin resistance gene.