GENE KNOCKOUT DATABASE
Viable
Fertile
Testicular atrophy
Endocrine gland dysplasia
Development of broad and unusual spectrum of tumors
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Yamasaki, 1996
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Tumor induction and tissue atrophy in mice lacking E2F-1.
Cell 85, 537-548 (1996) [96222296]
| Line Name | DNA Construct | ||
|---|---|---|---|
| 1. | E2F1 (+/-) | A murine E2F-1 genomic clone was isolated from a 129/Sv genomic library in lambda-FIXII (Stratagene) screened by hybridization using Gene-Screen (NEN) according to the i.... | |
| 2. | E2F-1 (+/-) | A 129 mouse genomic phage clone containing the E2F-1 gene was mapped to identify exon positions using the mouse E2F-1 cDNA sequence (Li et al. (1994), CIT:762437; A. Tal.... | |
| 3. | E2F1 (-/-) | A murine E2F-1 genomic clone was isolated from a 129/Sv genomic library in lambda-FIXII (Stratagene) screened by hybridization using Gene-Screen (NEN) according to the i.... | |
| 4. | E2F-1 (-/-) |
|
