Enx (Hox 11 L1)

Absence or severe reduction of TCR gamma locus gene rearrangement
Development of megacolon
Massive distention of proximal colon
Increase in the number of myenteric ganglia, total neurons per ganglion and NADPH diaphorase presumtive inhibitory neurons per ganglion in the proximal and distal colon but decreased in distal ileum

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