Fos B

Normal phenotype and normal number of T and B cells

Gruda, 1996

Expression of FosB during mouse development: normal development of FosB knockout mice.
Oncogene 12, 2177-2185 (1996) [96218667]
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( (cd40))

	Line Name	DNA Construct
1.	CD40 (-/-)	Castigli et al (1994) isolated from a 129 Sv genomic library a 13-kb genomic DNA and prepared a targeting construct that eliminated exons 7, 8 , and 9 (coding for the tr....
2.	vav (-/-)	An 8.1 kb BamHI fragment containing several exons of the vav gene homologous to the dbl proto-oncogene was isolated from a 129/Sv mouse genomic library. An e....
3.	vav (-/-)	Five independent vav genomic phage clones were obtained from a mouse strain 129 library in lambda FixII (Stratagene). Selected fragments were cloned into pUC18 construc....
4.	Hlx (-/-)	In the targeting vector, which has 7.5 kb of Hlx sequences in its left arm and 2.8 kb in its right, a neo(R) expression cassette containing a phosphoglycerol kinase-1 pr....