G protein-coupled receptor kinase 3 (GRK3)

 Loss of odorant receptor desensitization
 Lack of the fast agonist-induced desensitization

Reference:

Peppel K, Boekhoff I, McDonald P, Breer H, Caron MG, Lefkowitz RJ.: G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization. J Biol Chem 1997 Oct 10;272 (41):25425-25428.


METHODOLOGY ( FROM T-BASE)


Database Links

OMIM MEDLINE Citations Protein Links Gene Map GDB