Keratinocyte Growth Factor (KGF)(FGF7)
Matted or rough hair growth, similar to TGF-alpha and FGF5 knockouts
Hair shaft cell growth restricted
Epidermal growth and wound healing unaffected
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Guo, 1996
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Keratinocyte growth factor is required for hair development but not for wound healing.
Genes Dev. 10, 165-175 (1996) [96154042]
(View Citation format,Abstract format,MEDLARS format,ASN.1 format,Save As..., or 30 Related MEDLINE citations)
| Line Name | DNA Construct | |
|---|---|---|
| 1. | KGF (+/-) | An isogenic Sv-129 mouse genomic library was screened with a human KGF cDNA probe corresponding to partial exon 1 sequences. One of the resulting clones, mKGF-lambda1,.... |
| 2. | KGF (-/-) | An isogenic Sv-129 mouse genomic library was screened with a human KGF cDNA probe corresponding to partial exon 1 sequences. One of the resulting clones, mKGF-lambda1,.... |
| 3. | TGF-alpha (-/-) KGF | An isogenic Sv-129 mouse genomic library was screened with a human KGF cDNA probe corresponding to partial exon 1 sequences. One of the resulting clones, mKGF-lambda1,.... |
