LIF
Normal fertility
Failure in implantation
Reduced growth occurs in mice bearing embryo
| Line Name | DNA Construct | |
|---|---|---|
| 1. | Lif (+/-) | A 3,301-bp DNA fragment of the gene including all the known introns and exons of the two forms of LIF (soluble LIF-D and matrix-associated LIF-M) plus 571 bases of the c.... |
| 2. | LIF (-/-) | A partial copy of the LIF (leukaemia inhibitory factor) genomic gene in which the 5' end of the gene started at a |
| 3. | Lif (-/-) | A 3,301-bp DNA fragment of the gene including all the known introns and exons of the two forms of LIF (soluble LIF-D and matrix-associated LIF-M) plus 571 bases of the c.... |
| 4. | LIF (+/-) | A partial copy of the LIF (leukaemia inhibitory factor) genomic gene in which the 5' end of the gene started at a |
| 5. | PmuLIFCD2 TG.OM | The LIF minigene was constructed by using PCR to amplify a cDNA/genomic hybrid that contained exon 1 (encoding the leader peptide of the diffusible form of LIF), fused t.... |
