Major histocompatibility complex class II (MHC class II)


	Major histocompatibility complex class II (MHC class II) Normal development of CD4+ cells Impaired-normal breeding performance Near complete elimination of CD4+ lymphocytes in spleen and thymus Complete inability to respond to T cell-dependent antigens Reduced growth Rapid rejection of MHC II-deficient skin by normal recipients Cosgrove et al., 1991 Grusby et al., 1991 Auchincloss Jr. et al., 1993 Crump et al., 1993 Ladel et al., 1994 METHODOLOGY ( FROM T-BASE) Currently, there are no entries for MHC 2 knockout methodologies in mouse. PROTEIN SEQUENCE ( FROM SWISS-PROT) Currently, there is no protein sequence for MHC Class 2 in mouse.

Major histocompatibility complex class II (MHC class II)

Normal development of CD4+ cells
Impaired-normal breeding performance
Near complete elimination of CD4+ lymphocytes in spleen and thymus
Complete inability to respond to T cell-dependent antigens
Reduced growth
Rapid rejection of MHC II-deficient skin by normal recipients

Cosgrove et al., 1991
Grusby et al., 1991
Auchincloss Jr. et al., 1993
Crump et al., 1993
Ladel et al., 1994

METHODOLOGY ( FROM T-BASE)

Currently, there are no entries for MHC 2 knockout methodologies in mouse.

PROTEIN SEQUENCE ( FROM SWISS-PROT)

Currently, there is no protein sequence for MHC Class 2 in mouse.