Mullerian-inhibiting substance (MIS)
Full descent of testes
Normal production of functional sperm
Leydig cell hyperplasia
Development in males of female reproductive organs, interfering with sperm transfer to females and resulting in male infertility
| Line Name | DNA Construct | |
|---|---|---|
| 1. | MIS (+/-) | A 1.0 kb fragment encoding the C-termimal region of the rat MIS (Mullerian-inhibiting substance) gene was used as probe to isolate the mouse MIS gene from a B6 genomic l.... |
| 2. | MIS (-/-) | A 1.0 kb fragment encoding the C-termimal region of the rat MIS (Mullerian-inhibiting substance) gene was used as probe to isolate the mouse MIS gene from a B6 genomic l.... |
