N-myc

Defects in heart and lung
Death on days 10.5-12.5 of gestation

Moens et al., 1992
Moens et al., 1993
Charron et al., 1992
Stanton et al., 1992

((n-myc))

	Line Name	DNA Construct
1.	N-myc/neo (+/-)	ES cells were previouslsy generated (G00-347-952) in which a portion of the second exon of the N-myc gene was replaced with a neo(r) gene. The mutant N-myc allele lack....
2.	N-myc (9a/+)	The N-myc genomic clone was a gift from R. DePinho and F. Alt (G00-095-187). The targeting vector extends from an SstII site in intron 1 to an EcoRI
3.	N-myc/neo (-/-)	ES cells were previouslsy generated (G00-347-952) in which a portion of the second exon of the N-myc gene was replaced with a neo(r) gene. The mutant N-myc allele lack....
4.	N-myc (9a/9a)	The N-myc genomic clone was a gift from R. DePinho and F. Alt (G00-095-187). The targeting vector extends from an SstII site in intron 1 to an EcoRI
5.	N-myc (+/-)	To test for N-myc expression, poly(A)+ RNA was isolated from D3 Es cells and submitted to Northern blot analysis. A 2.9-kb N-myc transcript was detected in D3 cells, in....
6.	N-myc (-/-)	Drug resistant targeting vectors were constructed from the BamHI-EcoRI fragment of the N-myc genomic clone spanning the region from the middle of n....
7.	N-myc (-/-)	Drug resistant targeting vectors were constructed from the BamHI-EcoRI fragment of the N-myc genomic clone spanning the region from the middle of n....
8.	N-myc (+/-)	Drug resistant targeting vectors were constructed from the BamHI-EcoRI fragment of the N-myc genomic clone spanning the region from the middle of n....
9.	N-myc (-/-)	To test for N-myc expression, poly(A)+ RNA was isolated from D3 Es cells and submitted to Northern blot analysis. A 2.9-kb N-myc transcript was detected in D3 cells, in....