Neuropeptide Y (NPY)
Attenuation of obesity
Reduced fat intake
Increased energy expenditure
Less severly affected by diabetes
Less severly affected by sterility
Less severly affected by somatotrophic defects
Erickson JC, Hollopeter G, Palmiter RD: Attentuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y. Science 274, 1704-1707, 1996
| Line Name | DNA Construct | |
|---|---|---|
| 1. | NPY (+/-) | The mouse NPY (neuropeptide Y) gene was isolated from a 129 Sv genomic library using a rat NPY cDNA as a probe. Details of the construction of NPYKO4 are available upon.... |
| 2. | NPY (-/-) | The mouse NPY (neuropeptide Y) gene was isolated from a 129 Sv genomic library using a rat NPY cDNA as a probe. Details of the construction of NPYKO4 are available upon.... |
| 3. | NOS (-/-) | The mouse neuronal nitric oxide synthase (NOS) gene was cloned from a lambda genomic library using the rat cDNA clone (Bredt et al., 1991; G00-032-710) as a probe. The.... |
