p56lck protein tyrosine kinase and CD45 protein tyrosine phosphatase

 Decreased epidermal T cells
 Decreased levels of V gamma 3 TCR on surface of T cells
 Blockage of maturation of V gamma 3 thymocytes

Kawai et al, 1995


METHODOLOGY ( FROM T-BASE)

((protein tyrosine kinase))

Line Name DNA Construct
1. p56(lck) (+/-) The neomycin resistance gene(neo R) cassette contains 1.2 kb derived from the XhoI-SalI fragment of plasmid pMC1PolA (G00-354-270), and was inserte....
2. p56(lck) (+/-) The neomycin resistance gene(neo R) cassette contains 1.2 kb derived from the XhoI-SalI fragment of plasmid pMC1PolA (G00-354-270), and was inserte....
3. p56(lck) (-/-) The neomycin resistance gene(neo R) cassette contains 1.2 kb derived from the XhoI-SalI fragment of plasmid pMC1PolA (G00-354-270), and was inserte....
4. p56(lck) (-/-) The neomycin resistance gene(neo R) cassette contains 1.2 kb derived from the XhoI-SalI fragment of plasmid pMC1PolA (G00-354-270), and was inserte....


Database links: p56(lck)

OMIM MEDLINE Citations Protein Links Nucleotide Links Gene Map GDB MEDLINE Neighbors

Database links: CD45

OMIM MEDLINE Citations Protein Links Nucleotide Links Gene Map GDB MEDLINE Neighbors