Plasminogen activator inhibitor-1 (PAI-1)
Viable
No apparent macroscopic or microscopic histological abnormalities
Greater resistance to venous thrombosis
No impairment of hemostasis
Mild hyperfibrinolytic state
Carmeliet, Kieckens, et al., 1993
Carmeliet, Stassen, et al., 1993
| Line Name | DNA Construct | |
|---|---|---|
| 1. | PAI-1 (-/-) | The PAI-1 (Plasminogen Activator Inhibitor-1) gene was isolated from a BALB/c genomic library (Clontech Laboratories, Palo Alto, CA). 8.1 kb of total homology was inclu.... |
| 2. | PAI-1 (+/-) | The PAI-1 (Plasminogen Activator Inhibitor-1) gene was isolated from a BALB/c genomic library (Clontech Laboratories, Palo Alto, CA). 8.1 kb of total homology was inclu.... |
| 3. | PAI-1 (-/-) and hem | The PAI-1 (Plasminogen Activator Inhibitor-1) gene was isolated from a BALB/c genomic library (Clontech Laboratories, Palo Alto, CA). 8.1 kb of total homology was inclu.... |
