Perforin and Fas

 Impaired lytic activity on diverse target cells in vitro

Lowin et al, 1994


METHODOLOGY ( FROM T-BASE)

((perforin fas))

Line Name DNA Construct
1. perforin (-/-) To generate a disruption construct, a 6.1-kb EcoRI-SalI fragment of genomic DNA containing exons 2 and 3 of the perforin gene was isolated from the....


Database links: Perforin

OMIM MEDLINE Citations Protein Links Nucleotide Links Gene Map GDB MEDLINE Neighbors

Database links: FAS

OMIM MEDLINE Citations Protein Links Nucleotide Links Cardiff Human Gene Mutation Database Gene Map GDB MEDLINE Neighbors