Pkd1

 Enlarged cystic kidneys
 Pancreatic ductal cysts
 Pulmonary hypoplasia
 Kidney and pancreas defects
 Perinatal lethality

Reference:

Lu W, Peissel B, Babakhanlou H, Pavlova A, Geng L, Fan X, Larson C, Brent G, Zhou J.: Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1. Nat Genet 1997 Oct;17 (2):179-181.


METHODOLOGY ( FROM T-BASE)

Pkd1 (+/-) To construct the targeting vector, a 190-bp mouse genomic Pkd1 (polycystic kidney disease 1) DNA probe containing exon 38 was used to isolate P1 clones from a 129/Sv....
Pkd1 (-/-) To construct the targeting vector, a 190-bp mouse genomic Pkd1 (polycystic kidney disease 1) DNA probe containing exon 38 was used to isolate P1 clones from a 129/Sv....

Database Links

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