Plp

 Highly disordered multilayer myelin sheath
 Lack of apposition of the extracytoplasmic surfaces

 Lack of intraperiod dense line

 Profound reduction of conductive velocities of CNS axons

 Impaired neuromotor coordination

 Behavioral changes

Boison and Stoffel, 1994

METHODOLOGY ( FROM T-BASE)

Currently, there are no entries for Plp knockout methodologies in mouse.


Database links

OMIM MEDLINE Citations Protein Links Nucleotide Links Cardiff Human Gene Mutation Database Gene Map GDB Coriell Cell Line Repository MEDLINE Neighbors