Synapsin I
No apparent changes in well being
No apparent changes in gross nervous sytem function
Selective increase in paired pulse facilitation
No major alteration in other synaptic parameters such as long term potentiation
Normal development No gross anatomical abnormalities Mossy fiber long-term potentiation intact Smaller mossy fiber giant terminals Reduced number of synaptic vesicles Altered presynaptic structures
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Takei, 1995
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Synapsin I deficiency results in the structural change in the presynaptic terminals in the murine nervous system.
J. Cell Biol. 131, 1789-800 (1995) [96134028]
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