TGF-alpha

 Normal fertility
 Abnormalities in hair follicles
 Eye abnormalities

Luetteke et al., 1993


METHODOLOGY ( FROM T-BASE )

((tgf-alpha))

Line Name DNA Construct
1. MMTV-TGF-alpha #29 To construct pMMTV-TGF-alpha, the SV40 early promoter region in the vector pKCR (G00-311-340) was replaced by the complete MMTV LTR. A 925 bp human TGFA cDNA from the p....
2. TGF-alpha (+/-) To inactivate the mouse TGF-alpha gene, the fourth exon, which encodes both the third disulfide loop of the mature growth factor and the transmembrane domain of the prec....
3. MT-TGF-alpha line M The 917 bp cDNA encoding unprocessed human TGF-alpha (Transforming Growth Factor-alpha) was removed from the plasmid phTGF1-10-925 (a gift from Dr. Graeme I. Bell, G00-0....
4. MT-TGF-alpha line M The 917 bp cDNA encoding unprocessed human TGF-alpha (Transforming Growth Factor-alpha) was removed from the plasmid phTGF1-10-925 (a gift from Dr. Graeme I. Bell, G00-0....
5. MT-TGF-alpha line M The 917 bp cDNA encoding unprocessed human TGF-alpha (Transforming Growth Factor-alpha) was removed from the plasmid phTGF1-10-925 (a gift from Dr. Graeme I. Bell, G00-0....
6. MMTV-TGF-alpha #257 To construct pMMTV-TGF-alpha, the SV40 early promoter region in the vector pKCR (G00-311-340) was replaced by the complete MMTV LTR. A 925 bp human TGFA cDNA from the p....
7. MMTV-TGF-alpha #64 To construct pMMTV-TGF-alpha, the SV40 early promoter region in the vector pKCR (G00-311-340) was replaced by the complete MMTV LTR. A 925 bp human TGFA cDNA from the p....
8. TGF-alpha (-/-) To inactivate the mouse TGF-alpha gene, the fourth exon, which encodes both the third disulfide loop of the mature growth factor and the transmembrane domain of the prec....
9. MT-TGF-alpha line M The 917 bp cDNA encoding unprocessed human TGF-alpha (Transforming Growth Factor-alpha) was removed from the plasmid phTGF1-10-925 (a gift from Dr. Graeme I. Bell, G00-0....
10. MMTV-TGF-alpha #29 To construct pMMTV-TGF-alpha, the SV40 early promoter region in the vector pKCR (G00-311-340) was replaced by the complete MMTV LTR. A 925 bp human TGFA cDNA from the p....
11. AML 14 hepatocyte l The 917 bp cDNA encoding unprocessed human TGF-alpha (Transforming Growth Factor-alpha) was removed from the plasmid phTGF1-10-925 (a gift from Dr. Graeme I. Bell, G00-0....
12. AML 12 hepatocyte l The 917 bp cDNA encoding unprocessed human TGF-alpha (Transforming Growth Factor-alpha) was removed from the plasmid phTGF1-10-925 (a gift from Dr. Graeme I. Bell, G00-0....


Database links

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