Thy-1

Viable
Unimpaired spatial learning
Normal long-term potentiation (LTP) in CA1
Regional impairment of hippocampal formation
Impairment of LTP
Strong inhibition of LTP in dentate gyrus

( (thy1))

	Line Name	DNA Construct
1.	Thy-1 (+/-)	The Thy-1 (neuronal glycoprotein) gene was inactivated by inserting the 1.9-kb BstEII fragment from PGKneo cassette into the BstEII site of the thi....
2.	Thy-1 (-/-)	The Thy-1 (neuronal glycoprotein) gene was inactivated by inserting the 1.9-kb BstEII fragment from PGKneo cassette into the BstEII site of the thi....