Transthyretin

 Phenotypically normal
 Viable
 Fertile
 Depressed levels of serum retinol, retinol binding protein, and thyroid hormone

Episkopou et al., 1993


METHODOLOGY ( FROM T-BASE)

((transthyretin))

Line Name DNA Construct
1. ttr (+/-) The targeting vector contains a 5.9-kb AvrII-ScaI genomic fragment, including exons 1-3, the neo and the herpes simplex virus thymidine kinase (tk)....
2. ttr (-/-) The targeting vector contains a 5.9-kb AvrII-ScaI genomic fragment, including exons 1-3, the neo and the herpes simplex virus thymidine kinase (tk)....


Database links

OMIM MEDLINE Citations Protein Links Nucleotide Links Cardiff Human Gene Mutation Database Gene Map GDB Coriell Cell Line Repository MEDLINE Neighbors