Urate oxidase
Hyperuricemia
Urate nephropathy
Death before 4 weeks of age in more than half of the mice
| Line Name | DNA Construct | |
|---|---|---|
| 1. | Urate oxidase (+/-) | Genomic clones of the mouse urate oxidase gene were isolated from a C57BL/6J mouse genomic library by using a mouse cDNA probe, and the gene structure was characterized.... |
| 2. | Urate oxidase (-/-) | Genomic clones of the mouse urate oxidase gene were isolated from a C57BL/6J mouse genomic library by using a mouse cDNA probe, and the gene structure was characterized.... |
