BENIGN LESIONS MASQUERADING AS MALIGNANT MELANOMA; HOW TO RECOGNIZE THE IMPOSTER

SPITZ NEVUS
Histologic Features

Slide 10

Size
<6 mm

Shape
Symmetrical

Margins
Sharply circumscribed

Epidermal nests
Bunches of bananas, clefting artifact, uniformly spaced nonconfluent

Pagetoid spread
Limited, epidermis overlying dermal component

Intradermal pattern
Uniform maturation, no mitoses at base, no pushing deep margins

Cell type
Spindle and epithelioid, little melanin

Epidermal changes
Acanthosis, hyperkeratosis, kamino bodies