Epithelium
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- Features
- Large cells (1-2 times the size of acinar cells)
- Abundant eosinophilic, finely granular cytoplasm. Cytoplasm may be clear
- Single round nuclei
- Dispersed chromatin
- Prominent nucleoli
- Distinct cell borders
- Rare mitosis
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Arrangements
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- Organoid pattern
- Tightly packed groups of cells
- Occasional lumen
- Microcysts or cysts
- Lack of squamous metaplasia
Stroma
Fine fibrovascular stroma
May contain lymphoid infiltrate
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Slide 65
