FRONTIERS IN BIOSCIENCE;
HOT PAPERS; 1996



HOT PAPERS IN MEDICINE AND BIOLOGY (1996) Number of citations
1996
K.C. Malcolm, A.H. Ross, R-G. Qui, M. Symons, J.H. Exton, "Activation of rat liver phospholipase D by the small GTP-binding protein RhoA," Journal of Biological Chemistry, 269:25951-4, 1994. (Cited in nearly 80 publications through October 1996)

A. Strasser, A.W. Harris, T. Jacks, S. Cory, "DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2," Cell, 79:329-39, 1994. (Cited in more than 110 publications through October 1996)

R.A. Shimkets, D.G. Warnock, C.M. Bositis, C. Nelson-Williams, J.H. Hansson, M. Schambelan, J.R. Gill, S. Ulick, R.V. Milora, J.W. Findling, C.M. Canessa, B.C. Rossier, R.P. Lifton, "Liddle's syndrome: Heritable human hypertension caused by mutations of the beta subunit of the epithelial sodium channel," Cell, 79:407-14, 1994. (Cited in more than 70 papers as of October 1996)

S. Whitham, S.P. Dinesh-Kumar, D. Choi, R. Hehl, C. Corr, B. Baker, "The product of the tobacco mosaic virus resistance gene n: similarity to toll and the interleukin-1 receptor," Cell, 78:1101-15, 1994. (Cited in more than 75 publications through August 1996)

E.P. Smith, J. Boyd, G.R. Frank, H. Takahashi, R.M. Cohen, B. Specker, T.C. Williams, D.B. Lubahn, K.S. Korach, "Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man," New England Journal of Medicine,331:1056-61, 1994. (Cited in more than 50 publications as of August 1996)

J. Jen, J.W. Harper, S.H. Bigner, D.D. Bigner, N. Papadopoulos, S. Markowitz, J.K.V. Willson, K.W. Kinzler, B. Vogelstein, "Deletion of p16 and p15 genes in brain tumors," Cancer Research, 54:6353-8, 1994. (Cited in more than 100 publications through August 1996)

J.C. Xu, T.M. Foy, J.D. Laman, E.A. Elliott, J.J. Dunn, T.J. Waldschmidt, J. Elsemore, R.J. Noelle, R.A. Flavell, "Mice deficient for the CD40 ligand," Immunity, 1:423-31, 1994 (Cited in more than 80 publications as of August 1996)

K.L. Schmeichel, M.C. Beckerle, "The LIM domain is a modular protein-binding interface," Cell, 79:211-9, 1994. (Cited in nearly 50 publications through August 1996)

E.M. Connor, R.S. Sperling, R. Gelber, P. Kiselev, G. Scott, M.J. O'Sullivan, R. VanDyke, M. Bey, W. Shearer, R.L. Jacobson, E. Jimenez, E. O'Neill, B. Bazin, J.-F. Delfraissy, M. Culnane, R. Coombs, M. Elkins, J. Moye, P. Stratton, J. Balsley, "Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment," New England Journal of Medicine, 331:1173-80, 1994. (Cited in nearly 130 publications through June 1996)

J.R. Burke, M.S. Wingfield, K.E. Lewis, A.D. Roses, J.E. Lee, C. Hulette, M.A. Pericak-Vance, J.M. Vance, "The Haw River Syndrome: Dentatorubropallidoluysian atrophy (DRPLA) in an African-American family," Nature Genetics, 7:521-4, 1994. (Cited in nearly 60 publications as of June 1996)

K.H. Buetow, J.L. Weber, S. Ludwigsen, T. Scherpbier-Heddema, G.M. Duyk, V.C. Sheffield, Z. Wang, J.C. Murray, "Integrated human genome-wide maps constructed using the CEPH reference panel," Nature Genetics, 6:391-3, 1994. (Cited in more than 140 publications as of June 1996)

M. Søgaard, K. Tani, R.R. Ye, S. Geromanos, P. Tempst, T. Kirchhausen, J.E. Rothman, T. Söllner, "A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles," Cell, 78:937-48, 1994. (Cited in more than 60 publications through April 1996)

Y.P. Yang, F.A. Nunes, K. Berencsi, E. Gonczol, J.F. Engelhardt, J.M. Wilson, "Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis," Nature Genetics, 7:362-9, 1994. (Cited in more than 75 publications as of April 1996)

N.W. Kim, M.A. Piatyszek, K.R. Prowse, C.B. Harley, M.D. West, P.L.C. Ho, G.M. Coviello, W.E. Wright, S.L. Weinrich, J.W. Shay, "Specific association of human telomerase activity with immortal cells and cancer," Science, 266:2011-5, 1994. (Cited in nearly 80 publications through April 1996)

R.A. Steinman, B. Hoffman, A. Iro, C. Guillouf, D.A. Liebermann, M.E. Elhouseini, "Induction of p21 (WAF1/CIP1) during differentiation," Oncogene, 9:3389-96, 1994. (Cited in more than 40 publications as of February 1996)

T.A. Wynn, I. Eltoum, I.P. Oswald, A.W. Cheever, A. Sher, "Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology," Journal of Experimental Medicine, 179:1551-61, 1994. (Cited in nearly 50 publications as of February 1996)

K.M. Standifer, C.C. Chien, C. Wahlestedt, G.P. Brown, G.W. Pasternak, "Selective loss of delta-opioid analgesia and binding by antisense oligodeoxynucleotide to a delta-opioid receptor," Neuron, 12:805-10, 1994. (Cited in more than 30 publications as of February 1996)

H. Roelink, A. Augsburger, J. Heemskerk, V. Korzh, S. Norlin, A. Ruiz i Altaba, Y. Tanabe, M. Placzek, T. Edlund, T.M. Jessell, J. Dodd, "Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord," Cell, 76:761-75, 1994. (Cited in nearly 90 publications as of February 1996)

R. Shiang, L.M. Thompson, Y. Zhu, D.M. Church, T.J. Fielder, M. Bocian, S.T. Winokur, J.J. Wasmuth, "Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia," Cell, 78:335-42, 1994. (Cited in more than 70 publications as of February 1996)

W.J. Su, R.L. Woodward, A.M. Dziewonski, "Degree-12 model of shear velocity heterogeneity in the mantle," Journal of Geophysical Research -- Solid Earth, 99:6945-80, 1994. (Cited in more than 50 publications as of February 1996)

R.G. Crystal, N.G. McElvaney, M.A. Rosenfeld, C.-S. Chu, A. Mastrangeli, J.G. Hay, S.L. Brody, H.A. Jaffe, N.T. Eissa, C. Danel, "Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis," Nature Genetics, 8:42-51, 1994. (Cited in almost 50 publications through November 1995)

M.O. Hengartner, H.R. Horvitz, "C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2," Cell, 76:665-76, 1994. (Cited in nearly 125 publications through November 1995)

K.L. Rock, C. Gramm, L. Rothstein, K. Clark, R. Stein, L. Dick, D. Hwang, A.L. Goldberg, "Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules," Cell, 78:761-71, 1994. (Cited in nearly 70 publications through November 1995)

Y. Cho, S. Gorina, P.D. Jeffrey, N.P. Pavletich, "Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations," Science, 265:346-55, 1994. (Cited in more than 140 publications through November 1995)

Source: The Scientist"