FRONTIERS IN BIOSCIENCE;
GENOME CENTERS



A B C D E F G H I J K L M N O P Q R S T U V X Y Z

* Agricultural Biotechnology Information Center
  • Links to agricultural biotech-related WWW homepages and Gophers
  • Bibliographies and resource guides on a range of biotech topics
  • Miscellaneous publications such as resource lists, guides, and directories
  • Biotechnology education resources and links to other education sites
  • Biotechnology newsletters from around the country and the world
  • Biotechnology patents selected full-text patents and links to other patent resources
  • Other biotechnology documents, regulatory and policy information including news releases
  • Other non-federal biotechnology documents. A catch-all for miscellaneous reports and studies
  • Biotechnology software for downloading or previewing
  • Bovine Somatotropin - Related Documents including news releases, reports by government agencies, and full-text patents

* Agricultural Genome Information Server (AGIS)

  • Plant and domesticated animal genome data
  • Newsletters and other bibliography
  • ACEDB Documentation
  • Search for projects and researchers
  • Search the AGRICOLA, GRIN and GenoBase databases

* Australian National Genomic Information Service (ANGIS)

  • Online Mendelian Inheritance in Animals (OMIA)
  • Online Mendelian Inheritance in Man (OMIM)
  • information on ANGIS facilities.

* Australian National University (Molecular Biology)

  • many biological subjects including molecular biology
  • search a large range of databases
  • bibliographic information, software sources, newsgroups, other sites.

* Baylor College of Medicine Genome Center

  • Newsletter
  • YAC Data Searches - the most current YAC data from various sources
  • Biologist's Control Panel - biological databases, search tools and information
  • BCM Search Launcher - WWW sequence search and analysis software
  • BCM Sequence Annotation Server - annotate sequences locally or in Entrez
  • Genome Reconstruction Manager - manage data flow for cosmid DNA sequencing

* Belgian EMBNet Node

  • SRS searches, GCG interface, EMBNet News
* BioMolecular Engineering Research Center (BMERC)
  • Protein Sequence Analysis (PSA) E-mail Server
  • PLSearch database of homologous protein family patterns
  • ProLink, database of protein structure, homologs and functional pattern information

* Biotech Company List

  • comprehensive lists of biotech companies

* Canadian Genome Analysis and Technology Program (CGAT)

  • information resource and communications nexus for genomics research in Canada.
  • genomics databases and information
    • Chromosome X
    • C. elegans cosmid transgenics
    • the Organelle Genome Database (GOBASE)
    • Organelle Genome Megasequencing Program
    • Rose Worm lab
    • Sulfolobus solfataricus Genome Project
  • CGAT Medical, ethical, legal and social issues (MELSI)
  • contact list of troubleshooters willing to answer your technical questions
  • software archive

* CBA-IST (Genoa)

  • HyperCLDB
    • Cell Line Data Base
    • 3000 human and animal cell lines from European culture collections
  • Descriptions of Interlab Project databanks of biological materials,

* CBRG at ETHZ

  • Protein database searching service (sequence similarity, mass, ALLvsALL)
  • Darwin Computational Biochemistry Tool service

* Centro Nacional de Biotecnologia (CNB)

  • Spanish EMBNet node and Biotechnology Research Center in Madrid.

* CEPH (Fondation Jean Dausset)
The Centre d'Etudes du Polymorphisme Humain (CEPH) is a research laboratory created in 1984 by Professor Jean Dausset (Nobel Prize, medicine and physiology, 1980). This laboratory constructs maps of the human genome.

  • CEPH-Genethon integrated maps
  • CEPH genotype database

* Cold Spring Harbor Labs

  • CSHL publications information
  • CSHL meetings

* Columbia University Human Genome Project

  • Chromosome 13 data (YACs, cosmids, STSs, markers)

* Columbia University Linkage Analysis Web Server

  • linkage newsletter
  • linkage analysis course
  • list of linkage analysis software
  • user's guide to Linkage package

* Cooperative Human Linkage Center (CHLC)
The goal of the Cooperative Human Linkage Center is to develop statistically rigorous, high heterozygosity genetic maps of the human genome that are greatly enriched for the presence of easy-to-use PCR-formatted microsatellite markers.

  • Genetic maps showing the positions of genetic markers
    • Integrated Maps showing the position of genetic markers constructed using genotype data from the CEPH reference panel.
    • CHLC Marker Maps showing the positions of CHLC generated markers in various reference maps.
  • Search by name for information on markers.
    • Search by name for information on markers, including map location primer and pcr conditions, and sequence templates.
    • Likely locations of current CHLC markers, in Version 2.0 Skeletal Maps
    • Tables of CHLC markers characterized by linkage analysis.
    • List of full information on markers generated by CHLC
      • In Current Linkage Map
      • Candidate Linkage Markers
      • Somatic Cell Hybrid Assigned
    • Prior versions of the CHLC generated markers.
    • Marshfield CA-repeat Markers
      • Table of initial typing data
      • Table of sequence data
      • Table of PCR Primers
  • CHLC publications.
    • Science Maps and Data
    • Copies of the CHLC Newsletter
  • CHLC project information.

* CSMC Molecular Genetics Labs
The Molecular Genetics Laboratories at Cedars-Sinai Research Institute are headed by Dr. Julie R. Korenberg.

  • Integrated YAC/BAC/PAC Resource For the Human Genome
  • Chromosome 21 Phenotypic Mapping Project
  • Gene Mapping Projects on chromosome 21
    • BAC Contig of the Chromosome 21 Congenital Heart Disease Region
    • Progressive Myoclonus Epilepsy & Holoprosencephaly
    • fluorescence in situ hybridization (FISH)
    • cDNA Mapping Project

* Derwent

  • Commercial scientific information provider
  • Gene Therapy, Patent and product information

* DOE Human Genome Program

  • Information on the DOE projects
  • links to LANL, LBL, LLNL etc.
  • A primer on the basic science of the program
  • Human Genome Project resources and meetings

* European Bioinformatics Institute (EBI)

  • EBI Databases
    • EMBL Nucleotide Sequence Database
    • SWISS-PROT Protein Sequence Database
    • Bio Catalogue of Software
    • dbEST and dbSTS
    • Radiation Hybrid Database
    • IMGT Immunogenetics Database
    • FlyBase
  • Data Submissions
  • Database query/retrieval
  • Sequence Similarity Searches
  • Documentation and Software

* European Molecular Biology Laboratory (EMBL)

  • descriptions of activities at EMBL

* European Molecular Biology Network Information

  • descriptions of the European national nodes.

* Forest Genetics Dendrome Project

  • Dendrome database project.
  • Collection of laboratory protocols.
  • Directory of Forest Geneticists and Tree Breeders.

* Galton Laboratory

  • information on MRC Human Biochemical Genetics Unit and UCL Genetics & Biometry Dept.
  • Chromosome 9 Workshop reports, maps, contact addresses
  • Chromosome Y fingerprint data
  • linkage software

* Genestream at EERIE
The Southern France Human Genome Project Computing Resource Center

* Généthon

  • GenomeView - access to several public physical and genetic map data sources
  • CEPH/Généthon Physical Map

* Geneva University (ExPASy)
The ExPASy World Wide Web (WWW) molecular biology server of the Geneva University Hospital and the University of Geneva is dedicated to the analysis of protein and nucleic acid sequences as well as 2-D PAGE.

  • Search databases
    • SWISS-PROT - Annotated protein sequence database
    • PROSITE - Dictionary of protein sites and patterns
    • SWISS-2DPAGE - Two-dimensional polyacrylamide gel electrophoresis database
    • SWISS-3DIMAGE - 3D images of proteins and other biological macromolecules
    • ENZYME - Enzyme nomenclature database
    • SeqAnalRef - Sequence analysis bibliographic reference database
  • Tools and software packages
    • Tools - Access to protein analysis tools
    • Swiss-Shop - Sequence alerting system for SWISS-PROT
    • Swiss-Model - Automated knowledge-based protein modelling server
    • Melanie - Software packages for 2-D PAGE analysis (including the Melanie II tutorial)
  • 2-D PAGE services and courses
    • SWISS-2DSERVICE - Get your 2-D Gels performed according to Swiss standards
    • 2-D PAGE training - attend a one week course in Geneva
    • Technical information on 2-D PAGE (protocols)

* Genome Therapeutics Corporation (GTC)

  • Commercial organisation.
  • FTP data files of Sequence assembly test kits
  • Chromosome 10 physical mapping data

* GenomeNet, Japan
GenomeNet is a Japanese computer network for genome research and related research areas in molecular and cellular biology.

  • DBGET - linked database search of:
    • Bibliographic data (Medline, LITDB)
    • Sequences (GenBank, EMBL, SWISS-PROT, PIR, PRF, PDBSTR, Prosite)
    • Protein 3-D structures (PDB)
    • Protein mutation data (PMD)
    • Chemical compounds in enzyme reaction (LIGAND)
    • Amino acid indices (AA-Index)
    • Genome mapping data (GDB, OMIM)
  • Sequence interpretation tools
    • MOTIF (Sequence Motif Search)
    • BLAST (Sequence Homology Search)
    • PSORT (Prediction of Protein Sorting Signals)
    • TFSEARCH (Transcription Factor Binding Site Search)

* Harvard Biochemistry and Molecular Biology
Lists of databases

  • text search of sequence databases, Entrez, protein motifs (Blocks, Prosite)
  • Structural information and databases, 2D protein gels, codon usage tables.
  • 2D Protein Gels
  • Codon usage tables
  • Metabolic compund databases, EC Enzyme database

* Harvard Biological Laboratories - Genome Research

  • Lists of other genome sites
  • GCG Software documentation.
  • Genome databases: Arabidopsis, C.elegans, Drosophila, Human, Mouse, Prokaryote, Yeast
  • text search of sequence databases, Entrez, culture collections, ReBase
  • Internet resources and searching for information across the networks

* HGMP Resource Centre

  • This is the HGMP-RC's home page.

* IMAGE Consortium
The I.M.A.G.E. Consortium was initiated by four academic groups on a collaborative basis after informal discussions led to a common vision of how to achieve an important goal in the study of the human genome: the Integrated Molecular Analysis of Genomes and their Expression.

They share high-quality, arrayed cDNA libraries and place sequence, map, and expression data on the clones in these arrays into the public domain. From this information, they re-array the unique clones to form a "master array" which they hope will ultimately contain a representative cDNA from each and every gene in the genome. These clones are available free of any royalties, and may be used by anyone agreeing with their guidelines.

  • most of their clones are now from 20 different cDNA libraries
  • over 100,000 human cDNA clones are now arrayed
  • over 180,000 5' and/or 3' sequences have been deposited into dbEST
  • over 4,000 chromosomal assignments have been entered into GDB
  • the master array currently consists of over 25,000 distinct genes.

* InfoBioGen
Provides a computing and information resource to the French molecular biology and genome projects. Mainly in French.

* InfoBiotech Canada
InfoBiotech Canada is a partnership of government, private and academic sectors with the goal of providing enhanced access to information on biotechnology in Canada and worldwide.

The site contains several databases and other useful biotech information. There are a large number of other biotech sites that have been linked to. A search engine provides a method for searching the sites for particular information. Internet wide search engines are also provided to allow for internet wide searching.

* Indiana University (IUBio)
IUBio Archive is an archive of biology data and software. The archive includes items to browse, search and fetch molecular data, software, biology news and documents.

* Japan Animal Genome Databases

  • Genomic Database Search
    • Pig
      • Clickable Cytogenetic Map
      • Clickable USDA Linkage Map
      • Clickable PIGM Linkage Map
    • Cattle
      • Clickable Cytogenetic Map
      • Clickable USDA Linkage Map
    • Chicken
      • Clickable Cytogenetic Map
      • Clickable Linkage Map
    • Horse
      • Clickable Cytogenetic Map
  • Japanese Dairy Cattle Improvement Program
  • National Insitute of Animal Industry

* Japan Down Syndrome Network (JDSN)
This is a information center for Down Syndrome in Japan.

  • links to other disability and handicap associations around the world
  • help for parents of Down's Syndrome children

* Johns Hopkins Bio-informatics WWW server

  • Protein Databases
    • OWL - a non-redundant protein sequence database which ties a number of databases together.
    • NRL_3D - a sequence--structure database.
    • PIR(1-3) - The Protein Identification Resource Protein sequence database.
    • EC-Enzyme - An Enzyme classification database.
    • GenQuest - rapid and sensitive comparison of DNA and Protein sequences.
    • REBASE - The Restriction Enzyme Database
  • Electronic Publications for Biology
    • Primer on Molecular Genetics
    • Mathematics and Biology
    • DOE Whitepaper on Bio-Informatics
    • Report: NCHGR GESTEC Directors' Meeting on Genome Informatics
  • Other Biological Databases
    • TBASE The Transgenic/Targeted Mutation Database
    • The Developmental Studies Hybridoma Bank
    • The Millipore On-line Catalog
    • The DOE Human Subjects Database

* Johns Hopkins GDB WWW server

  • The GDB Browser
  • OMIM - Online Mendelian Inheritance in Man
  • Ideogram-Based Searching of GDB
  • Maps of HUGO Reference Markers
  • Further information about GDB and its future developments

* Kansas University Medical Center Genetics Education Center
For educators interesed in human genetics and the human genome project

* LANL Biosciences

  • Sigma chromosome maps
  • Chromosome 16 flat file
  • HIV Databases
  • Nucleic Acid MOdeling Tool(NAMOT)

* Lawrence Berkeley Lab (LBL) Human Genome Center

  • Human Chromosome 21 P1 and cDNA mapping databases
  • Drosophila physical mapping
  • Instrumentation and informatics projects
  • Human chromosome and directed genome sequencing projects

* LLNL Human Genome Center

  • Detailed maps of human chromosome 19
  • Information on LLNL mapping projects
  • Information on IMAGE - Integrated Molecular Analysis of Genomes and their Expression.

* Meat Animal Research Center (MARC)

  • Pig and cattle genome data with clickable maps.

* MendelWeb

  • Commentary on Mendel's papers

* Michigan Human Genome Center

  • DNA Sequencing
  • On-line documentation
  • Whitehead/MIT Mouse Map Data
  • CEPH-Généthon physical map data

* Minnesota University Medical School, Computational Biology Centers

  • Information on Arabidopsis, Corn, Rice, Loblolly Pine & Zebrafish Sequence Analysis Projects
  • PCR in situ information
  • Genetic Linkage Analysis information
  • Virtual Genome Centre
  • Candida albicans molecular biology
  • Neuroscience Database Program
  • Staden, GCG, OSP and Zuker's Mfold Software on-line Manuals

* Minnesota University Institute of Human Genetics
Description of projects and services at the Institute of Human Genetics.

  • Molecular Genetics
  • Genetic Services:
    • Molecular Genetics Laboratory
    • Microchemical Facility
    • Gene Therapy
  • Clinical Genetics
  • Developmental Biology
  • Behavioral Genetics
  • Genetic Epidemiology
  • Career Training

* Missouri University - Maize Genome Database : MaizeDB

  • Maize Genetic Maps

* Mosquito Genomics WWW Server

  • Aedes aegypti linkage and physical maps and AaeDB database
  • Anopheles gambiae database (AaeDB)
  • FlyBase
  • mosquito images

* Motif BioInformatics Server
Lists of other sites and databases.

* Moulon

  • C. elegans ACeDB-style genome database.
  • Integrated Genome Database (IGD)
  • Metabolic database (by Stan Letovsky)
  • information on setting up ACeDB databases on WWW

* Mouse and Rat Research Home Page

  • rodent genome databases and other information.

* National Center for Biotechnology Information (NCBI)
The NCBI is responsible for building, maintaining, and distributing GenBank, the NIH genetic sequence database that collects all known DNA sequences from scientists worldwide.

  • text search of Genbank, dbEST, dbSTS, Entrez
  • submitting sequences to GenBank (BankIt)
  • Blast sequence similarity search

* National Center for Genome Resources (NCGR)
The National Center for Genome Resources is a not-for-profit organization created to design, develop, support, and deliver resources in support of public and private genome research.

  • GSDB Genome sequence database with hyperlinks to GDB, SwissProt etc.
  • SIGMA system for integrated genome map assembly
  • Ethical, Legal, and Social Implications of Biotechnology (ELSI) information

* NIH - National Institutes of Health
NIH information, News and Events, Health information, Grants and Contracts, Scientific resources, Institutes and Offices.

* NIH GenoBase Server
GenoBase is a Prolog-based, object-oriented molecular biology database. This installation incorporates and links the contents of several large datasets, including EMBL and Swiss-Prot. While operations are still experimental, we are now providing a gateway for World Wide Web users to a substantial subset of the data in our GenoBase installation.

  • text/accession number search of EMBL, SwissProt, EC data, Prosite
  • Selkov Metabolic Pathway Database
  • Mycoplasma capricolum Genome Project data
  • Genbank text and BLAST searches

* OncoLink - The University of Pennsylvania Cancer Resource
Not a genome centre exactly, but has useful stuff on oncology. Aims to provide one-stop shopping for the patient, healthcare provider, researcher or Internet browser searching for cancer-related information. Keyword search of oncology literature.

* Organelle Genome Megasequencing Program (OGMP)

  • Organelle genome information and databases
  • protist image database

* Pasteur Institute

  • Pasteur Institute projects
  • many databases and useful sites

* Philadelphia Genome Center

  • Human Chromosome 22 information

* QUEST Protein Database Centre

  • 2D Gel Protein databases, especially of Yeast
  • Yeast Protein Database (YPD)
  • Gel related software

* Reference Library DataBase (RLDB)

  • search RLDB database (hybridisation and PCR) results of work of filters of cosmid, YAC, P1 and cDNA libraries.
  • list of other sites

* Research Genetics

  • commercial organisation
  • provides a large variety of reagents and biological materials
  • their catalogue holds items from Adenovirus RNA 1 Probe, to YAC Library Custom Screening
  • new service: MAPPAIRS (microsatellite markers consisting of a pair of PCR primers which flank a simple sequence repeat that is polymorphic)

* Roslin Institute

  • genome databases: PiGMaP, BovMaP and ChickMap
  • comparative mapping database TCAGdb
  • wide range of sequence databases and tools
  • good list of genome databases

* Saccharomyces Genomic Information Resource

  • Saccharomyces Genomic Information & Databases
  • Information on completed Yeast chromosome sequencing projects
  • BLAST and FASTA searches against the Saccharomyces Genome Database (SGD)

* Sanger Centre

  • Information on the Sanger Centre and local projects
  • Information on ACeDB and its derivative databases
  • Wormpep: Predicted proteins from the C. elegans project
  • Prodom: Protein Domain Database
  • List of biological Web servers

* SEQNET

  • U.K. molecular biology site and U.K. node of EMBnet.
  • list of sequence and genomic databases

* Stanford Human Genome Center

  • FTP data files of STSs, mapping data, chromosome 4 radiation-hybrid mapping, YAC STS-content mapping project
  • soon to have WWW searches of this data

* Texas University Health Science Center

  • Human chromosome 3 database - STSs and YACs
  • Human chromosome 3 sensitive genetic map
  • Human chromosome 3 cytogenetic breakpoint map

* TIGR (The Institute for Genomic Research)

  • a not-for-profit research center
  • EST database information
  • Haemophilus influenzae Rd Genome database (HIDB)
  • Sequences, Sources, Taxa database (SST)

* Tokyo University

  • information on the insect group
  • genetic maps of Bombyx mori.

* Utah University

  • Mostly local information and descriptions of projects
  • STS database

* USDA/ARS/NAL Plant Genome Data

  • plant genome newsletter.
  • calendar of events.
  • plant DNA libraries.
  • information on plant genome mapping projects.
  • plant genome grant information.

* Virtual Genome Centre

  • sequence analysis tools:
    • Primer selection for PCR
    • translation
    • codon usage
    • protein motifs
    • Oligo Tm determination
    • atypical sequences
    • human repeats
    • dot plots
  • Query Genbank, SwissProt databases
  • useful databases and tables:
    • codons
    • size of human chromosomes
    • human repeated DNA
  • Sequences of the S. cerevisiae chromosomes
  • Genome program news and gossip
  • Candida albicans: physical map, sequence data, strains, resources

* WWW Virtual Library: Biosciences (Harvard)

  • Impressive, large list of other sites.

* Washington University Genome Sequencing Center

  • Caenorhabditis elegans sequencing
  • EST sequencing as part of the Washington University & Merk Co. EST Project

* Washington University Institute for Biomedical Computing (IBC)

  • C. elegans genome data
  • Human chromosome X data
  • Biochemical compound database (Klotho)
  • lists of other resources

* Washington University, Dept of Pathology

  • Human idiograms
  • graphical locus query of GDB
  • scanned images of human and mouse chromosome spreads

* WEHI - The Walter and Eliza Hall Institute of Medical research

  • GCG Programs and Manuals
  • MHCPEP Database
  • SRS
  • Malaria Database
  • PDBBrowse: A Graphics Interface to the Brookhaven Protein Data Bank
  • GDB Human Genome Data Base

* Weizmann Institute Bio-Informatics

  • List of genome & molecular biology sites
  • Bibliographic sources
  • BioMOO (interactive meeting place for biologists)

* Whitehead Institute/MIT Genome Center

  • Human YAC screening data for sequence tagged sites (STSs) screened on the CEPH mega-YAC library with over 1100 contigs assembled using double linkage between STSs.
  • For each STS, they report addresses for the YACs found to contain the STS.
  • Human, Rat and Mouse marker map data files.