VASOPRESSIN SIGNALING PATHWAYS IN VASCULAR SMOOTH MUSCLE

Raphael A. Nemenoff

Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262

Received 1/21/98 Accepted 2/4/98

TABLE OF CONTENTS

1. Abstract

2. Introduction

3. Physiologic effects of vasopressin in smooth muscle

4. Post-receptor signaling pathways

4.1. Mobilization of intracellular Ca²⁺
4.2. Regulation of protein kinase pathways
4.3. Regulation of arachidonic acid release and eicosanoid production

5. Effects on gene expression

5.1. Immediate early response genes 5.2. Smooth muscle-alpha-actin

6. Other effectors

7. Conclusion and further directions

8. Acknowledgments

9. References

10. Entire manuscript