[Frontiers in Bioscience 8, d855-869, May 1, 2003]
FUNCTION OF BONE MORPHOGENETIC PROTEIN SIGNALING DURING MOUSE DEVELOPMENT
Molecular Developmental Biology Section, Laboratory of Reproductive and Developmental Toxycology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 USA
Figure 1. BMP receptors are membrane bound Ser/Thr kinases
Figure 2. Binding Specifity of the TGF-beta superfamily receptors.
Figure 3. Constitutece Active Type I receptors send signals without ligands or type II receptors. Dominant Negative Type I receptors block BMP signaling.
Figure 4. Function of BMP signaling in L-R asymmetry.