[Frontiers in Bioscience , -0, June , 00]

Nonsurgical treatment options in the management of intracranial meningiomas

Shervin R. Dashti1, Eric Sauvageau1, Kris A. Smith1, Lynn S. Ashby2

1Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, 350 W. Thomas Road, Phoenix, Arizona 85013, 2Division of Neurology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, 350 W. Thomas Road, Phoenix, Arizona 85013

FIGURES

Figure 1. Postcontrast T1-weighted MR images of a 56-year-old man presenting with a rapidly growing extraaxial lesion (A) found to be consistent with a Grade II anaplastic meningioma (B) after gross total resection. Six months later, the patient had a massive recurrence at the site of resection (C) and diffusely in the posterior fossa (D). Despite aggressive surgical resection and radiation treatment, he died of his disease within 3 months.

Figure 2. The Gamma Knife stereotactic radiosurgery unit. A fixed headframe system allows radiation to be delivered precisely to targeted intracranial regions.