[Frontiers in Bioscience E1, 587-599, June 1, 2009]

Surgical treatment of meningiomas

Nicholas C. Bambakidis1, Peter Nakaji2

1Department of Neurological Surgery, The Neurological Institute, University Hospital Case Medical Center, 11100 Euclid Avenue, Cleveland, OH, 44106, 2 Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, 350 W. Thomas Road, Phoenix, Arizona, 85013


1. Abstract
2. Introduction
3. Surgery for meningiomas
3.1. Anterior fossa meningiomas
3.2. Olfactory groove meningiomas
3.3. Tuberculum sellae meningiomas
3.4. Middle fossa meningiomas
3.5. Lateral sphenoid wing
3.6. Medial sphenoid wing
3.7. Midline cranial vault meningiomas
3.8. Posterior fossa meningiomas
3.9. Petroclival region meningiomas
4. Conclusions
5. References


Meningiomas, though benign histologically, are relatively common tumors that may behave in an aggressive, clinical fashion. Traditionally, treatment for these lesions has been primarily through surgical excision. This may be curative, but it has become clear that the degree of surgical resection achieved is a primary determinant of the rate of tumor recurrence. Often, the size and location of the lesion is a limiting factor during surgery. The following article describes general principles of surgical treatment as well as some of the pitfalls inherent in treating meningiomas in specific intracranial locations.