[Frontiers in Bioscience S3, 372-384, January 1, 2011]

Roles of phytochemicals in amino acid nutrition

Xiangfeng Kong1, Guoyao Wu1-3, Yinlong Yin1

1Hunan Engineering and Research Center of Animal and Poultry Science and Key Laboratory for Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, the Chinese Academy of Sciences, Changsha, Hunan, China 410125, 2Department of Animal Science, Texas A&M University, College Station, TX, USA 77843, 3State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing, China 100193


1. Abstract
2. Introduction
3. Amino Acid composition in typical Chinese herbs 4. Effects of dietary supplementation with Chinese herbal powder on ileal digestibilities of amino acids in weaned piglets
5. Effects of dietary supplementation with Acanthopanax senticosus extracts on ileal digestibilities of amino acids in weaned piglets
6. Effects of dietary supplementation with Astragalus polysaccharide on ileal digestibilities of amino acids in weaned piglets
7. Effects of dietary supplementation with glycyrrhetinic acid on endogenous arginine provision in early-weaned piglets
8. Effects of steroidal saponin from Yucca schidigera extract (BIOPOWDER) on intestinal arginase activity
9. Summary and perspective
10. Acknowledgements
11. References


Chinese herbal medicine (CHM) is often used as dietary supplements to maintain good health in animals and humans. Here, we review the current knowledge about effects of CHM (including ultra-fine Chinese herbal powder, Acanthopanax senticosus extracts, Astragalus polysaccharide, and glycyrrhetinic acid) as dietary additives on physiological and biochemical parameters in pigs, chickens and rodents. Additionally, we propose possible mechanisms for the beneficial effects of CHM on the animals. These mechanisms include (a) increased digestion and absorption of dietary amino acids; (b) altered catabolism of amino acids in the small intestine and other tissues; (c) enhanced synthesis of functional amino acids (e.g., arginine, glutamine and proline) and polyamines; and (d) improved metabolic control of nutrient utilization through cell signaling. Notably, some phytochemicals and glucocorticoids share similarities in structure and physiological actions. New research findings provide a scientific and clinical basis for the use of CHM to improve well-being in livestock species and poultry, while enhancing the efficiency of protein accretion. Results obtained from animal studies also have important implications for human nutrition and health.