Hematologic values

 

 

TYPICAL REFERENCE INTERVALS

COMPONENT

CONVENTIONAL UNITS

FACTOR

RECOMMENDED SI UNITS

ANTITHROMBIN III

  • Immunologic

20-30 mg/dL

10

200-300 mg/L

  • Funcitonal

80-120 U/dL

10

800-1200 U/L

ACTIVATED PARTIAL THROMBOPLASTIN TIME (APTT)

Depends on activator and phospholipid reagents used, typically 25-35 s

BLEEDING TIME

Depends on location and orientation of cut and on particular device, typically 2-8 min.

CLOT LYSIS TIME

  • Euglobulin factor

1 - 4 h at 37C

  • Whole blood

None by 24 h at 37C

CLOT REACTION

Complete by 4 h at 37C

COAGULATION FACTORS

0.50-1.50 /mL

1000

500-1500 U/L

ERYTHROCYTE INDICES

 

  • Mean corpuscular volume (MCV)

80-96 m3

1

80-96 fL

  • Mean corpuscular hemoglobin (MCH)

27.5-33.2 pg

1

27.5-33.2 pg

  • Mean corpusculear hemoglobin concentration (MCHC)

33.4-35.5%

0.01

Concentration fraction: 0.334-0.355

FACTOR XIII (SCREENING TEST)

Clot insoluble in 5 mol/L urea at 24 h

HEMATOCRIT

  • Male

41.5-50.4%

0.01

Volume fraction: 0.415-0.504

  • Female

35.9-44.6%

 

Volume fraction: 0.359-0.446

HEMOGLOBIN

  • Male

14.0-17.5 g/dL

10

140-175 g/L

  • Female

12.3-15.3 g/dL

 

123-153 g/L

HEMOGLOBIN A2

1.5-3.5% of total hemoglobin

0.01

mass fraction: 0.015-0.035 of total hemoglobin

HEMOGLOBIN F

<2%

0.01

mass fraction: <0.02

OSMOTIC FRAGILITY

 

% Lysis

% NaCl-171

Lysis-0.01

Lysed Fraction

 

% (w/v) NaCl

Fresh

24 h at 37C

 

NaCl mmol/L

Fresh

24 h at 37C

 

0.2

-

95-100

 

34.2

-

0.95-1.00

 

0.3

97-100

85-100

 

51.3

0.97-1.00

0.85-1.00

 

0.35

90-99

75-100

 

59.8

0.90-0.99

0.75-100

 

0.4

50-95

65-100

 

68.4

0.50-0.95

0.65-1.00

 

0.45

5-45

55-95

 

77.0

0.05-0.45

0.55-0.95

 

0.5

0.6

40-85

 

85.5

0-0.06

0.40-0.85

 

0.55

-

15-70

 

94.1

0

0.15-0.70

 

0.6

-

0-40

 

102.6

-

0-0.40

 

0.65

-

0-10

 

111.2

-

0-0.10

 

0.7

-

0-5

 

119.7

-

0-0.05

 

0.75

-

0

 

128.3

-

0

PLASMA D-DIMERS

<200 ng/mL

1

<200 g/L

PLASMA VOLUME

  • Male

 25-43 mL/kg body weight

0.001

0.025-0.043 L/kg body weight

  • Female

 28-45 mL/kg body weight

 

 

0.028-0.045 L/kg body weight

PLASMINOGEN

  • Immunologic

10-20 mg/dL

10

100-200 mg/L

  • Functional

80-120 U/dL

10

800-1200 U/L

PLATELET COUNT

150,000-450,000/L

106

150-450 x 109/L

PROTEIN C

0.7 - 1.4 /mL

10

700-1400 U/L

PROTEIN S (TOTAL)

0.7 - 1.4 /mL

10

700-1400 U/L

PROTHROMBIN TIME

Depends on thromboplastin reagent used, typically 10-13 s

RED CELL VOLUME

  • Male

20-36 mL/kg body weight

0.001

0.020-0.036 L/kg body weight

  • Female

19-32 mL/kg body weight

 

 

0.019-0.032 L/kg body weight

RED CELL COUNT

  • Male

4.5-5.9 x 106/L

106

4.5-5.9 x 1012/L

  • Female

4.5-5.1 x 106/L

 

4.1-5.1 x 1012/L

RETICULOCYTE COUNT

0.5-1.5%

0.01

Number fraction: 0.005-0.015

 

 

25,000-75,000 cells/L

106

25-75 x 109/L

SEDIMENTATION RATE (ESR) (WESTERGREN)

  • Men under 50 years

<15 mm/h

 

 

 

  • Men 50 - 85 years

<20 mm/h

 

 

 

  • Men over 85 years

<30 mm/h

 

 

 

  • Women under 50 years

<20 mm/h

 

 

 

  • Women over 50 - 85 years

<30 mm/h

 

 

 

  • Women over 85 years

<42 mm/h

 

 

 

THROMBIN TIME

Depends on concentration of thrombin reagent used, typically 17-25 s

VON WILLEBRAND FACTOR

  • Immunologic

50-150 U/dL

10

500-1500 U/L

  • Ristocetin cofactor activity

50-150 U/dL

10

500-1500 U/L

VISCOSITY

1.4-1.8 times water

1

1.4-1.8 times water

WHITE CELL COUNT

4.4-11.0 x 103/L

106

4.4-11.3 x 109/L

WHITE BLOOD CELL DIFFERENTIAL (ADULT)

 

MEAN PERCENT

RANGE OF ABSOLUTE COUNTS

FACTOR

MEAN NUMBER RANGE OF

FRACTION* ABSOLUTE COUNT

  • Segmented neutrophils

56%

1800-7800/L

106

0.56 1.8-7.8 x 109/L

  • Bands

3%

0-700/L

106

0.03 0-0.70 x 109/L

  • Eosinophils

2.7%

0-450/L

106

0.027 0-0.45 x 109/L

  • Basophils

0.3%

0-200/L

106

0.003 0-0.20 x 109/L

  • Lymphocytes

34%

1000-4800/L

106

0.34 1.0-4.8 x 109/L

  • Monocytes

4%

0-800/L

106

0.04 0-0.80 x 109/L

ZETA SEDIMENTATION RATIO

41-54%

0.01

Fraction: 0.41-0.54